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Trade Name	Drug Name	Approved	Patent Expires	Indication
Benznidazole	Benznidazole	2017-08-29		Chagas disease , Bacterial infections , Protozoan infections
Estradiol	Estradiol	2022-08-10	2024-2037	Prostatic neoplasms , Breast neoplasms , Menorrhagia , Contraception , Primary ovarian insufficiency , Hot flashes , Hypogonadism , Premature menopause , Acne vulgaris , Leiomyoma , Endometriosis , Endometrial hyperplasia , Uterine hemorrhage , Amenorrhea , Female infertility , Delayed puberty , Renal cell carcinoma , Endometrial neoplasms , Hypoventilation
Nuvessa	Metronidazole	2014-03-24	2024-2039	Rosacea , Bacterial infections , Giardiasis , Helicobacter infections , Surgical wound infection , Abscess , Bacterial vaginosis , Bacterial endocarditis , Bacterial meningitis , Protozoan infections , Amebiasis , Pseudomembranous enterocolitis , Trichomonas vaginitis , Bacteroides infections , Acne vulgaris , Nausea , Virus diseases , Diarrhea , Gonorrhea , Cholera , Escherichia coli infections , Campylobacter infections , Bacillary dysentery , Chlamydia infections , Bronchitis , Streptococcal infections , Dyspepsia , Bartonella infections , Bacterial eye infections , Syphilis , Staphylococcal infections , Stomach diseases , Borrelia infections , Rickettsia infections , Mycoplasma infections , Chancroid , Granuloma inguinale , Psittacosis

Clinical Trials

Therapeutic Areas:

All

Classification:

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Approval:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Estradiol benzoate

healthy volunteers/patients

,

,

bronchiolitis obliterans syndrome

,

,

trypanosomiasis

,

,

Estradiol valerate

healthy volunteers/patients

,

hematologic neoplasms

,

,

,

uterine hemorrhage

,

,

,

,

,

,

,

atopic dermatitis

,

myeloid leukemia acute

,

multiple myeloma

,

,

plasma cell neoplasms

,

large b-cell lymphoma diffuse

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

opioid-related disorders

,

alzheimer disease

,

huntington disease

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

,

,

triple negative breast neoplasms

,

serogroup b neisseria meningitidis

,

,

urologic neoplasms

,

urinary bladder neoplasms

,

urologic diseases

,

urinary bladder diseases

,

,

,

cognitive dysfunction

,

central nervous system neoplasms

,

solitary fibrous tumors

,

neurofibromatosis 1

,

neurofibromatoses

,

hemangioblastoma

,

hemangiopericytoma

,

,

streptococcal infections

,

thyroid neoplasms

,

thyroid diseases

,

,

breast neoplasms

,

sickle cell anemia

,

,

renal insufficiency

,

,

,

rheumatoid arthritis

,

,

bacterial pneumonia

,

juvenile arthritis

,

psoriatic arthritis

,

ankylosing spondylitis

,

carotid artery diseases

,

atherosclerosis

,

ulcerative colitis

,

,

meningococcal meningitis

,

,

thromboembolism

,

,

,

acquired immunodeficiency syndrome

,

immune reconstitution inflammatory syndrome

,

,

alopecia areata

,

,

,

healthy volunteers/patients

,

,

communicable diseases

,

intraabdominal infections

,

smoking cessation

,

neuroendocrine tumors

,

islet cell adenoma

,

psychomotor agitation

,

,

renal cell carcinoma

,

,

gaucher disease

,

tobacco use disorder

,

,

brain neoplasms

,

nutritional status

,

,

pneumococcal pneumonia

,

,

male breast neoplasms

,

respiratory tract infections

,

embryo transfer

,

,

,

,

postpartum hemorrhage

,

inflammatory bowel diseases

,

,

tendon injuries

,

,

community-acquired infections

,

haemophilus influenzae

,

streptococcus pneumoniae

,

prostatic neoplasms

,

,

energy metabolism

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

neoplasms by site

,

non-small-cell lung carcinoma

,

,

falciparum malaria

,

,

renal cell carcinoma

,

colorectal neoplasms

,

,

healthy volunteers/patients

,

,

,

multiple myeloma

,

pancreatic neoplasms

,

uterine cervical neoplasms

,

squamous cell carcinoma of head and neck

,

,

type 1 diabetes mellitus

,

sickle cell anemia

,

sjogren's syndrome

,

,

,

respiration disorders

,

chronic hepatitis b

,

endometrial neoplasms

,

plasma cell neoplasms

,

malignant mesothelioma

,

cutaneous malignant melanoma

,

streptococcus agalactiae

,

follicular lymphoma

,

microsatellite repeats

,

small cell lung carcinoma

,

macular degeneration

,

b-cell lymphoma

,

,

,

,

respiratory tract diseases

,

,

focal segmental glomerulosclerosis

,

cytomegalovirus infections

,

membranous glomerulonephritis

,

nephrotic syndrome

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

systemic scleroderma

,

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

kidney transplantation

,

,

,

,

b-cell chronic lymphocytic leukemia

,

beta-thalassemia

,

,

sickle cell trait

,

,

,

clear cell adenocarcinoma

,

large cell carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

,

breast neoplasms

,

,

ovarian neoplasms

,

rheumatoid arthritis

,

haemophilus influenzae type b

,

haemophilus infections

,

,

chronic renal insufficiency

,

,

neisseria meningitidis

,

respiratory syncytial virus infections

,

streptococcal infections

,

,

muscle spasticity

,

kidney diseases

,

postmenopausal osteoporosis

,

non-hodgkin lymphoma

,

,

human influenza

,

,

,

insulin resistance

,

pneumococcal infections

,

thrombocytopenic purpura idiopathic

,

inflammatory breast neoplasms

,

ductal carcinoma breast

,

,

,

,

abdominal obesity

,

,

,

,

chronic kidney failure

,

,

large b-cell lymphoma diffuse

,

,

renal insufficiency

,

systemic lupus erythematosus

,

myocardial infarction

,

st elevation myocardial infarction

,

acute coronary syndrome

,

,

,

left ventricular hypertrophy

,

rotavirus infections

,

,

,

meningococcal infections

,

,

mucinous adenocarcinoma

,

,

meningococcal meningitis

,

,

thrombocytopenia

,

respiratory syncytial viruses

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

,

,

chronic obstructive pulmonary disease

,

acquired immunodeficiency syndrome

,

,

,

,

,

metabolic bone diseases

,

obstructive lung diseases

,

pulmonary eosinophilia

,

,

,

chronic bronchitis

,

,

chronic disease

,

growth and development

,

,

,

immunologic tests

,

,

alzheimer disease

,

cardiovascular diseases

,

wasting syndrome

,

,

lipid metabolism

,

resistance training

,

,

,

major depressive disorder

,

depressive disorder

,

,

allergic rhinitis seasonal

,

clostridioides difficile

,

,

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

,

pulmonary edema

,

,

squamous cell carcinoma

,

squamous cell neoplasms

,

prostatic neoplasms

,

peritoneal neoplasms

,

breast neoplasms

,

,

,

ovarian neoplasms

,

acquired immunodeficiency syndrome

,

,

communicable diseases

,

neoplasm metastasis

,

,

,

premature obstetric labor

,

,

ovarian epithelial carcinoma

,

overactive urinary bladder

,

non-small-cell lung carcinoma

,

chronic renal insufficiency

,

kidney diseases

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

,

,

head and neck neoplasms

,

renal cell carcinoma

,

,

urinary tract infections

,

,

non-hodgkin lymphoma

,

fallopian tube neoplasms

,

endometrial neoplasms

,

erectile dysfunction

,

,

muscle spasticity

,

urinary incontinence

,

,

postmenopausal osteoporosis

,

stomach neoplasms

,

gastrointestinal neoplasms

,

acute coronary syndrome

,

,

parkinson disease

,

respiratory tract diseases

,

orthomyxoviridae infections

,

human influenza

,

,

,

brain neoplasms

,

small cell lung carcinoma

,

,

venous thrombosis

,

thrombophlebitis

,

,

postoperative nausea and vomiting

,

post-traumatic stress disorders

,

traumatic stress disorders

,

,

,

,

triple negative breast neoplasms

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

immunologic deficiency syndromes

,

atherosclerosis

,

,

,

systemic lupus erythematosus

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

Globulin, immune

prostatic neoplasms

,

chronic obstructive pulmonary disease

,

,

chronic bronchitis

,

,

,

graft vs host disease

healthy volunteers/patients

,

,

hemolytic-uremic syndrome

,

kidney diseases

,

,

,

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