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Trade Name	Drug Name	Approved	Patent Expires	Indication
Benznidazole	Benznidazole	2017-08-29		Chagas disease , Bacterial infections , Protozoan infections
Estradiol	Estradiol	2022-08-10	2024-2037	Prostatic neoplasms , Breast neoplasms , Menorrhagia , Contraception , Primary ovarian insufficiency , Hot flashes , Hypogonadism , Premature menopause , Acne vulgaris , Leiomyoma , Endometriosis , Endometrial hyperplasia , Uterine hemorrhage , Amenorrhea , Female infertility , Delayed puberty , Renal cell carcinoma , Endometrial neoplasms , Hypoventilation , Abdominal pain
Nuvessa	Metronidazole	2014-03-24	2024-2039	Rosacea , Bacterial infections , Giardiasis , Helicobacter infections , Surgical wound infection , Abscess , Bacterial vaginosis , Bacterial endocarditis , Bacterial meningitis , Protozoan infections , Amebiasis , Pseudomembranous enterocolitis , Trichomonas vaginitis , Bacteroides infections , Acne vulgaris , Nausea , Virus diseases , Diarrhea , Gonorrhea , Cholera , Escherichia coli infections , Campylobacter infections , Bacillary dysentery , Chlamydia infections , Bronchitis , Streptococcal infections , Dyspepsia , Bartonella infections , Bacterial eye infections , Syphilis , Staphylococcal infections , Stomach diseases , Borrelia infections , Rickettsia infections , Mycoplasma infections , Chancroid , Granuloma inguinale , Psittacosis

Clinical Trials

Therapeutic Areas:

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Classification:

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Approval:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

embryo transfer

Estradiol benzoate

,

embryo transfer

healthy volunteers/patients

,

,

bronchiolitis obliterans syndrome

,

,

trypanosomiasis

,

,

Estradiol valerate

ovarian neoplasms

,

ovarian epithelial carcinoma

,

triple negative breast neoplasms

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

,

hereditary sensory and autonomic neuropathies

,

,

endometrial neoplasms

,

invasive hydatidiform mole

,

,

,

breast neoplasms

,

multiple endocrine neoplasia type 1

,

beta-thalassemia

,

,

myeloid leukemia

,

healthy volunteers/patients

,

ulcerative colitis

,

,

,

rheumatoid arthritis

,

myeloid leukemia acute

,

atopic dermatitis

,

hidradenitis suppurativa

,

,

,

,

pathologic constriction

,

inflammatory bowel diseases

,

intestinal diseases

brain neoplasms

,

nutritional status

,

,

pneumococcal pneumonia

,

,

male breast neoplasms

,

respiratory tract infections

,

embryo transfer

,

,

,

,

postpartum hemorrhage

,

inflammatory bowel diseases

,

,

tendon injuries

,

,

community-acquired infections

,

haemophilus influenzae

,

streptococcus pneumoniae

,

prostatic neoplasms

,

,

energy metabolism

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

neoplasms by site

,

non-small-cell lung carcinoma

,

,

falciparum malaria

,

,

ovarian neoplasms

,

renal cell carcinoma

,

colorectal neoplasms

,

,

healthy volunteers/patients

,

,

,

multiple myeloma

,

pancreatic neoplasms

,

uterine cervical neoplasms

,

squamous cell carcinoma of head and neck

,

,

type 1 diabetes mellitus

,

sickle cell anemia

,

sjogren's syndrome

,

,

,

respiration disorders

,

chronic hepatitis b

,

endometrial neoplasms

,

plasma cell neoplasms

,

malignant mesothelioma

,

cutaneous malignant melanoma

,

streptococcus agalactiae

,

follicular lymphoma

,

microsatellite repeats

,

small cell lung carcinoma

,

macular degeneration

,

b-cell lymphoma

,

,

,

,

respiratory tract diseases

,

,

focal segmental glomerulosclerosis

,

cytomegalovirus infections

,

membranous glomerulonephritis

,

nephrotic syndrome

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

systemic scleroderma

,

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

kidney transplantation

,

,

,

,

b-cell chronic lymphocytic leukemia

,

beta-thalassemia

,

,

sickle cell trait

,

,

,

clear cell adenocarcinoma

,

large cell carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

,

breast neoplasms

,

,

rheumatoid arthritis

,

haemophilus influenzae type b

,

haemophilus infections

,

,

chronic renal insufficiency

,

,

neisseria meningitidis

,

respiratory syncytial virus infections

,

streptococcal infections

,

,

muscle spasticity

,

kidney diseases

,

postmenopausal osteoporosis

,

non-hodgkin lymphoma

,

,

human influenza

,

,

,

insulin resistance

,

pneumococcal infections

,

thrombocytopenic purpura idiopathic

,

inflammatory breast neoplasms

,

ductal carcinoma breast

,

,

,

,

abdominal obesity

,

,

,

,

chronic kidney failure

,

,

large b-cell lymphoma diffuse

,

,

renal insufficiency

,

systemic lupus erythematosus

,

myocardial infarction

,

st elevation myocardial infarction

,

acute coronary syndrome

,

,

,

left ventricular hypertrophy

,

rotavirus infections

,

,

,

meningococcal infections

,

,

mucinous adenocarcinoma

,

,

meningococcal meningitis

,

,

thrombocytopenia

,

respiratory syncytial viruses

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

,

,

chronic obstructive pulmonary disease

,

acquired immunodeficiency syndrome

,

,

,

,

,

metabolic bone diseases

,

obstructive lung diseases

,

pulmonary eosinophilia

,

,

,

chronic bronchitis

,

,

chronic disease

,

growth and development

,

,

,

immunologic tests

,

,

alzheimer disease

,

cardiovascular diseases

,

wasting syndrome

,

,

lipid metabolism

,

resistance training

,

,

,

major depressive disorder

,

depressive disorder

,

,

allergic rhinitis seasonal

,

clostridioides difficile

,

threatened abortion

,

knee osteoarthritis

,

Globulin, immune

inflammatory breast neoplasms

,

,

,

,

,

oligodendroglioma

,

small cell lung carcinoma

,

paroxysmal hemoglobinuria

,

,

systemic lupus erythematosus

,

microsatellite repeats

,

stomach neoplasms

,

neoplasm metastasis

,

non-hodgkin lymphoma

,

esophageal neoplasms

,

hodgkin disease

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

liver neoplasms

,

squamous cell carcinoma of head and neck

,

,

,

hepatocellular carcinoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

pancreatic neoplasms

,

prolymphocytic leukemia

,

prostatic neoplasms

,

ovarian neoplasms

,

bronchiolitis obliterans syndrome

,

hypercholesterolemia

,

h1n1 subtype influenza a virus

,

biliary tract neoplasms

,

renal cell carcinoma

,

,

,

triple negative breast neoplasms

,

head and neck neoplasms

,

atopic dermatitis

,

basal cell carcinoma

,

basal cell neoplasms

,

heart transplantation

,

aplastic anemia

,

fallopian tube neoplasms

,

rectal neoplasms

,

pancreatic ductal carcinoma

,

induction chemotherapy

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

renal insufficiency

,

brain neoplasms

,

follicular lymphoma

,

,

lymphoid leukemia

,

meningococcal meningitis

,

neisseria meningitidis

,

west nile fever

,

systemic scleroderma

,

diffuse scleroderma

,

refractory anemia with excess of blasts

,

refractory anemia

,

esophageal squamous cell carcinoma

,

uterine cervical neoplasms

,

,

,

paraproteinemias

,

monoclonal gammopathy of undetermined significance

,

ovarian epithelial carcinoma

,

squamous cell carcinoma

,

squamous cell neoplasms

,

prolymphocytic leukemia t-cell

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

uveal neoplasms

,

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

,

hyperlipoproteinemia type ii

,

,

t-cell lymphoma peripheral

,

laryngeal neoplasms

,

stem cell transplantation

,

colonic neoplasms

,

multiple myeloma

,

breast neoplasms

,

,

non-small-cell lung carcinoma

,

,

b-cell chronic lymphocytic leukemia

,

colorectal neoplasms

,

myelodysplastic syndromes

,

plasma cell neoplasms

,

,

myeloid leukemia acute

,

,

graft vs host disease

,

,

,

meningococcal infections

,

human influenza

,

,

hematologic neoplasms

,

,

graft rejection

,

,

bcr-abl positive chronic myelogenous leukemia

,

rheumatoid arthritis

,

thrombotic thrombocytopenic purpura

,

immune system diseases

,

,

haemophilus influenzae type b

,

reperfusion injury

,

,

neuroendocrine tumors

,

carcinoid tumor

,

,

paraneoplastic syndromes

,

islet cell carcinoma

,

islet cell adenoma

,

,

,

somatostatinoma

,

respiratory hypersensitivity

,

,

,

glomerulonephritis

,

haemophilus infections

,

myeloid leukemia

,

autoimmune diseases

,

nervous system diseases

,

autoimmune diseases of the nervous system

,

demyelinating diseases

,

cns demyelinating autoimmune diseases

,

myeloproliferative disorders

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

multiple sclerosis

,

,

,

relapsing-remitting multiple sclerosis

,

kidney transplantation

,

,

chronic kidney failure

,

,

,

type 1 diabetes mellitus

,

,

glycogen storage disease type ii

,

,

liver transplantation

,

psychology rejection

,

transplantation

,

immunosuppression therapy

,

,

glycogen storage disease type iii

,

,

mucopolysaccharidosis i

,

kidney diseases

,

diabetes mellitus

,

b-cell leukemia

,

,

clostridium infections

,

vaccine immunogenicity

,

pathologic processes

,

healthy volunteers/patients

healthy volunteers/patients

,

,

hemolytic-uremic syndrome

,

kidney diseases

,

,

,

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