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Trade Name	Drug Name	Approved	Patent Expires	Indication
Benznidazole	Benznidazole	2017-08-29		Chagas disease , Bacterial infections , Protozoan infections
Estradiol	Estradiol	2022-08-10	2024-2037	Prostatic neoplasms , Breast neoplasms , Menorrhagia , Contraception , Primary ovarian insufficiency , Hot flashes , Hypogonadism , Premature menopause , Acne vulgaris , Leiomyoma , Endometriosis , Endometrial hyperplasia , Uterine hemorrhage , Amenorrhea , Female infertility , Delayed puberty , Renal cell carcinoma , Endometrial neoplasms , Hypoventilation
Nuvessa	Metronidazole	2014-03-24	2024-2039	Rosacea , Bacterial infections , Giardiasis , Helicobacter infections , Surgical wound infection , Abscess , Bacterial vaginosis , Bacterial endocarditis , Bacterial meningitis , Protozoan infections , Amebiasis , Pseudomembranous enterocolitis , Trichomonas vaginitis , Bacteroides infections , Acne vulgaris , Nausea , Virus diseases , Diarrhea , Gonorrhea , Cholera , Escherichia coli infections , Campylobacter infections , Bacillary dysentery , Chlamydia infections , Bronchitis , Streptococcal infections , Dyspepsia , Bartonella infections , Bacterial eye infections , Syphilis , Staphylococcal infections , Stomach diseases , Borrelia infections , Rickettsia infections , Mycoplasma infections , Chancroid , Granuloma inguinale , Psittacosis

Clinical Trials

Therapeutic Areas:

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Classification:

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Approval:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

ovulation inhibition

,

Estradiol benzoate

ovulation inhibition

,

Estradiol valerate

ovulation inhibition

,

,

,

atopic dermatitis

,

myeloid leukemia acute

,

multiple myeloma

,

,

plasma cell neoplasms

,

large b-cell lymphoma diffuse

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

opioid-related disorders

,

alzheimer disease

,

huntington disease

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

,

,

triple negative breast neoplasms

,

serogroup b neisseria meningitidis

,

,

urologic neoplasms

,

urinary bladder neoplasms

,

urologic diseases

,

urinary bladder diseases

,

,

,

cognitive dysfunction

,

central nervous system neoplasms

,

solitary fibrous tumors

,

neurofibromatosis 1

,

neurofibromatoses

,

hemangioblastoma

,

hemangiopericytoma

,

,

streptococcal infections

,

thyroid neoplasms

,

thyroid diseases

,

,

breast neoplasms

,

sickle cell anemia

,

,

renal insufficiency

,

,

,

rheumatoid arthritis

,

,

bacterial pneumonia

,

juvenile arthritis

,

psoriatic arthritis

,

ankylosing spondylitis

,

carotid artery diseases

,

atherosclerosis

,

ulcerative colitis

,

,

meningococcal meningitis

,

,

thromboembolism

,

,

,

acquired immunodeficiency syndrome

,

immune reconstitution inflammatory syndrome

,

,

alopecia areata

,

,

,

healthy volunteers/patients

,

,

communicable diseases

,

intraabdominal infections

,

smoking cessation

,

neuroendocrine tumors

,

islet cell adenoma

,

psychomotor agitation

,

,

renal cell carcinoma

,

,

gaucher disease

,

tobacco use disorder

,

,

complex regional pain syndromes

,

,

,

,

,

,

stress urinary incontinence

,

,

prostatic hyperplasia

,

choroidal neovascularization

,

,

diabetes mellitus

,

magnetic resonance imaging

,

,

,

hypertrophic cicatrix

,

,

major depressive disorder

,

carpal tunnel syndrome

,

premature ejaculation

,

,

rectal neoplasms

,

low anterior resection syndrome

,

,

penile induration

,

thoracic outlet syndrome

,

postherpetic neuralgia

,

motor neuron disease

,

thyroid diseases

,

,

ovarian neoplasms

,

stomach neoplasms

,

head and neck neoplasms

,

esophageal neoplasms

,

,

urinary bladder neoplasms

,

small cell lung carcinoma

,

endophthalmitis

,

lacrimal apparatus diseases

,

,

radiation injuries

,

uveal neoplasms

,

,

pancreatic neoplasms

,

macular degeneration

,

,

breast neoplasms

,

myofascial pain syndromes

,

neurogenic urinary bladder

,

,

,

,

,

non-small-cell lung carcinoma

,

dystonic disorders

,

temporomandibular joint disorders

,

,

,

somatoform disorders

,

systemic scleroderma

,

raynaud disease

,

diffuse scleroderma

,

urinary bladder diseases

,

multiple sclerosis

,

,

postoperative pain

,

breast diseases

,

hereditary breast and ovarian cancer syndrome

,

,

,

,

patellofemoral pain syndrome

,

allergic conjunctivitis

,

,

muscle spasticity

,

overactive urinary bladder

,

urinary incontinence

,

migraine disorders

,

,

,

,

healthy volunteers/patients

,

,

,

dry eye syndromes

,

,

prostatic neoplasms

,

diabetic retinopathy

,

parkinson disease

,

,

,

,

,

chronic kidney failure

,

renal insufficiency

,

iron-deficiency anemia

,

iron deficiencies

,

,

interstitial cystitis

,

graves ophthalmopathy

,

,

,

spinal cord injuries

,

developmental disabilities

,

,

,

left ventricular hypertrophy

,

,

sjogren's syndrome

,

retinal vein occlusion

,

herpes labialis

,

traumatic brain injuries

,

,

,

,

keratoconjunctivitis sicca

,

,

,

muscle strength

,

clostridium botulinum type a

healthy volunteers/patients

,

,

pheochromocytoma

,

neuroendocrine tumors

,

,

meningeal carcinomatosis

,

,

laryngeal neoplasms

,

pancreatic ductal carcinoma

,

,

head and neck neoplasms

,

squamous cell neoplasms

,

transitional cell carcinoma

,

malignant pleural effusion

,

fallopian tube neoplasms

,

small cell carcinoma

,

psychological inhibition

,

gastrointestinal neoplasms

,

dna repair-deficiency disorders

,

urinary bladder neoplasms

,

salivary gland neoplasms

,

,

,

radiation injuries

,

radiation effects

,

germ cell and embryonal neoplasms

,

peritoneal neoplasms

,

,

pleural effusion

,

,

residual neoplasm

,

breast neoplasms

,

type 2 diabetes mellitus

,

diabetes mellitus

,

neoplasm metastasis

,

,

,

prostatic neoplasms

,

,

,

small cell lung carcinoma

,

triple negative breast neoplasms

,

gastroesophageal reflux

,

,

,

,

,

rheumatoid arthritis

,

castration-resistant prostatic neoplasms

,

ovarian neoplasms

,

neoplasms by site

,

,

major depressive disorder

,

depressive disorder

,

,

peptic esophagitis

,

,

colorectal neoplasms

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

renal cell carcinoma

,

endometrial neoplasms

,

stomach neoplasms

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

urologic neoplasms

,

,

,

kidney diseases

,

,

cardiovascular diseases

,

pancreatic neoplasms

,

ovarian epithelial carcinoma

,

breast diseases

,

sickle cell anemia

,

brain neoplasms

,

,

,

opioid-induced constipation

,

,

hypercholesterolemia

,

biliary tract neoplasms

,

gallbladder neoplasms

,

disease progression

,

hereditary breast and ovarian cancer syndrome

,

,

chronic renal insufficiency

,

,

,

glucose metabolism disorders

,

metabolic diseases

,

endocrine system diseases

,

hypersensitivity

,

,

kidney neoplasms

,

,

zollinger-ellison syndrome

,

,

peptic ulcer hemorrhage

,

,

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

anxiety disorders

,

,

venous thrombosis

,

pulmonary embolism

,

plexiform neurofibroma

,

neurofibromatosis 1

,

unknown primary neoplasms

,

respiratory insufficiency

,

myocardial infarction

,

coronary artery disease

,

bile duct neoplasms

,

cholangiocarcinoma

,

,

respiratory syncytial virus infections

,

uterine neoplasms

,

b-cell lymphoma

,

esophageal neoplasms

,

non-small-cell lung carcinoma

,

,

,

respiratory tract diseases

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

thoracic neoplasms

,

bronchial neoplasms

Globulin, immune

healthy volunteers/patients

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

macular degeneration

,

,

,

monoclonal gammopathy of undetermined significance

,

,

soft tissue neoplasms

,

,

chronic hepatitis b

,

,

,

herpesviridae infections

,

,

,

plasmablastic lymphoma

,

large-cell lymphoma immunoblastic

,

,

renal cell carcinoma

,

urologic neoplasms

,

kidney neoplasms

,

neoplasm metastasis

,

essential thrombocythemia

,

primary myelofibrosis

,

precursor cell lymphoblastic leukemia-lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

aplastic anemia

,

,

prostatic neoplasms

,

non-small-cell lung carcinoma

,

hematologic neoplasms

,

,

hidradenitis suppurativa

,

smoldering multiple myeloma

,

immunoglobulin light-chain amyloidosis

,

renal insufficiency

,

atopic dermatitis

,

,

,

,

,

paraproteinemias

,

,

,

castration-resistant prostatic neoplasms

,

,

ovarian neoplasms

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

adenocarcinoma of lung

,

biliary liver cirrhosis

,

peripheral arterial disease

,

castleman disease

,

alzheimer disease

,

,

cognitive dysfunction

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

hematologic diseases

,

bone marrow diseases

,

,

cytokine release syndrome

,

small cell carcinoma

,

small cell lung carcinoma

,

neuroendocrine carcinoma

,

,

,

,

,

diffuse intrinsic pontine glioma

,

optic nerve glioma

,

brain stem neoplasms

,

,

acquired immunodeficiency syndrome

,

retroviridae infections

,

viral sexually transmitted diseases

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

sickle cell anemia

,

residual neoplasm

,

plasma cell neoplasms

,

rheumatoid arthritis

,

non-hodgkin lymphoma

,

b-cell lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

large b-cell lymphoma diffuse

,

,

juvenile arthritis

,

colorectal neoplasms

,

systemic lupus erythematosus

,

follicular lymphoma

,

mantle-cell lymphoma

,

axial spondyloarthritis

,

,

lymphoid leukemia

,

waldenstrom macroglobulinemia

,

b-cell lymphoma marginal zone

,

,

prolymphocytic leukemia t-cell

,

neonatal alloimmune thrombocytopenia

,

,

multiple myeloma

,

,

,

,

psoriatic arthritis

,

ulcerative colitis

,

,

ankylosing spondylitis

,

inflammatory bowel diseases

,

spondylarthropathies

,

spondylarthritis

,

,

cardiovascular diseases

,

chronic kidney failure

,

pure red-cell aplasia

,

,

kidney diseases

,

,

congenital abnormalities

,

autoimmune diseases

,

,

lymphoproliferative disorders

healthy volunteers/patients

,

,

hemolytic-uremic syndrome

,

kidney diseases

,

,

,

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